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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Let’s never spend our New Year apart.让我们永不独享新年。
吕特回应称:“这就是坐在沙发上发推特与治理国家的区别。如果你在治理这个国家,你就得做明智的决定,而驱逐大使是不明智的。”

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

进入2月以来,猛龙逐渐感到他们需要进行人员调整了:良好的开局已经被挥霍的差不多了,他们的防守不足以限制对手,他们在四号位有个巨大的漏洞,在凯尔-洛瑞即将成为自由球员之前,他们急迫的需要利用好他的巅峰期。
Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

不过巴蒂表示,中国大学排名的稳定并不值得担忧。他说:“数十年的持续投资建设以及中国高等教育国际化程度的提高,无疑将使得中国的大学变得越来越好。”

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

5. 弗莱德·赫什三人组(Fred Hersch Trio),《漂浮》(Floating), Palmetto。赫什目前的钢琴三人组由约翰·艾伯特(John Hébert)担任贝斯,埃里克·麦克菲森(Eric McPherson)担任鼓手,他们有着精确的优雅。这张专辑的结构如同一场夜间俱乐部演出,包括若干重新编配的标准曲,以及几首强劲而充满情感的原创曲,有着强大的表现力。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

While British schools moved up two places on average, French schools, the largest group from any one country, fell one place on average. EMLyon Business School dropped outside the MBA ranking and lost 15 places overall, while Edhec Business School failed to make it into the Executive MBA ranking and lost eight places overall as a result.
While heavily dominated by French and English schools, accounting for 44 per cent of the table, the ranking is more diverse than ever with schools from 25 countries.
Susan Chan, head of iShares Asia-Pacific at BlackRock, says ETFs are more popular among institutional investors in the region.
不会。华尔街策略师预测美国政府的10年期借贷成本将在未来一年攀升至3%以上,这话就像尴尬的办公室聚会一样是圣诞节那段时间的固定节目。鉴于美联储退出量化宽松和美国减税,今年的预测看起来更有可能实现。然而,压低通胀和长期债券收益率的长期重大因素依然存在,并且仍然被低估。2018年美联储将至少加息三次,但10年期收益率不会突破3%。

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 莫让“以房养老”变了味
Perspective

Trends and targets in antiviral phototherapy

extravagant
He added that “almost every major Korean company, including Hyundai Motor and AmorePacific, relies heavily on Chinese sales”.
而或许更引人关注的问题是,雅虎究竟为何决定拿出3,000万美元来收购一款手机应用呢?诚然,Summly的文本精炼能力与新战略下的雅虎对移动设备的侧重不谋而合。伴随着以11亿美元对轻博客的收购,以及广受好评的新款天气应用的推出,Summly软件的加入见证了雅虎占领智能手机领域的坚定决心,以及为爱使手机的年轻消费者提供优质服务的不懈努力。
Price growth in top cities was slower, however, with Beijing, for instance, reporting a rise of only 0.5 per cent from the previous month, compared to 4.9 per cent in September.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

今年最佳的季中交易早已发生了:

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

韩语用户设置的"你的出生地"猜10次就能成功破译的概率是39%。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

2017年度国家公务员考试网上报名于上周六开始。
Despite such arguments from a handful of scientists, the vast majority of those who study the climate say the earth is in a long-term warming trend that is profoundly threatening and caused almost entirely by human activity.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

May the beauty and joy of New Year remain with you throughout the new year!愿新春美景与欢乐常伴随你!
[di't?:min]

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

James Bond Themes 5. "Live and Let Die" by Paul McCartney and Wings
"No one really knows how (end times) would look and how God would bring it about," Cox said.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

“为什么这件事发生在我女儿身上?”她说,“因为枪支造成的死亡太多了,我不知道还要死多少人。”
Google's top 10 searches for 2017–U.S.
Most Catholics (60 percent) and white non-evangelical Protestants (65 percent) say they believe disasters like hurricanes and floods are the result of climate change.
伯利兹城最富盛名的旅游胜地莫过于巨大的水下天坑--蓝色巨洞以及玛雅遗址。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 威宁西南水泥余热发电运行并网
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Télécom Business School in France and Prague’s University of Economics have the most gender-balanced faculty, with exactly 50 per cent women, while Switzerland’s University of Zurich is the least balanced, with only 9 per cent. Switzerland’s IMD has the most international faculty, with 94 per cent of them from overseas, while faculty at Politecnico di Milano School of Management are all Italian.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Last year, the Education Ministry issued a booklet warning Korean high school students of 'plastic surgery syndrome', citing Michael Jackson and a local woman whose addiction to plastic surgery left her with a grotesquely swollen face.
欧洲管理学院协会(Cems)管理硕士项目——由30家商学院联合提供的国际项目——排名第九,比2015年下滑五名。该项目上一次上榜是在2015年。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

两岸是骨肉同胞,血浓于水,不管岛内形势如何变化,都割断不了两岸的亲情,也改变不了我们维护两岸关系和平发展的决心和诚意。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

在出售给Facebook前,WhatsApp一直特别反对植入广告。该公司首席执行官让o库姆在自己桌上一直贴着联合创始人布莱恩o阿克顿留下的一张便条,随时提醒自己牢记公司的核心价值观:“不要广告!不要游戏!不要宣传噱头!”这样一来,短信应用只好想出别的创意。比如Tango就在用户的短信“收件箱”里插入广告。中国互联网巨头腾讯公司旗下的短信应用——微信,则通过游戏、贴纸(类似于表情符号)和移动购物等方式谋取赚钱之道。Kik则提供一种被一些人称为“聊天广告”的功能,用户通过它能和幽默网站Funny or Die及电影信息网站Moviefone这类品牌运营的聊天程序进行交谈。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

CONTACT: Staci Donegan and Peter Westley, Celia Dunn Sotheby’s International Realty, (912) 247-2052 / (912) 660-5169; celiadunnsir.com
[.k?ntri'bju:n]
对于可治疗的癌症,非洲人有了新的希望。
对于更多的普通投资者而言,在标普500指数回报高于历史平均值的大背景下,2014年是充满挫折的一年。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

“如果30年前的改革是解决意识形态问题,现在则要解决利益问题。改革是调整既得利益,等于拿刀割自己的肉,很痛苦,需要下定决心、坚定信心。”
2.You Never Have a Day When You Wake Up Excited To Go To Work
供给侧结构性改革初见成效;
RSPCA inspectors found 13 dead cats and an emaciated survivor when they raided the property in Adelaide, South Australia, in September 2015.
《何以笙箫默》

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

PRICE PER SQUARE FOOT: $310
Democratic frontrunner Hillary Clinton says that if she's elected president, at least half of her Cabinet will be women.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

22岁的吉吉·哈迪德和21岁的贝拉·哈迪德也是首次跻身榜单,分别位列榜单的第五位和第九位,吉吉·哈迪德的收入为950万美元,她的妹妹贝拉·哈迪德的收入为600万美元。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

都柏林大学学院(UCD)迈克尔?斯墨菲特商业研究生院(Michael Smurfit Graduate School of Business)的总体进步最大,排名攀升21位至第48名。北京大学(Peking University)光华管理学院(Guanghua School of Management)重回排行榜第38名,去年该院因学员调查反馈率低而未上榜。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

n. 行星
经济学人智库全球生活成本指数发现,亚洲和澳大利亚共有11个城市跻身全球最贵20城市之列,其余有8个是欧洲城市,一个为南美城市。北美没有一个城市进入前20名。
adj. 投影的,投射 v. 投射(project的过去
《初来乍到》(Fresh off the Boat),ABC,2月4日播出。这部喜剧是根据大厨与美食、旅游真人秀主持人黄颐铭的回忆录改编的,讲述20世纪90年代中期的佛罗里达,一个华裔美国家庭克服文化冲突,努力适应美国生活的故事。哈德逊·杨(Hudson Yang)饰演迷恋嘻哈乐的11岁男孩艾迪,在《采访》(The Interview)中饰演金正恩的兰道尔·朴(Randall Park)饰演他的父亲,一位郊区牛排餐厅骄傲的店主。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

"Hiring a veteran can be one of the best decisions any of us can make, and Wal-Mart is proud that we have hired more than 26,000 since we announced our Welcome Home Commitment on Memorial Day," Simon told Fortune. "Veterans have a strong record of performance under pressure and passion for service, which makes our pledge to hire, learn from, and support them easy."
因为吉吉·哈迪德和凯蒂·派瑞等多位模特和表演者在申请签证时遇到了一系列问题,维密秀的主办方正试图使一切回到正轨,如今主办方又表示,中国政府还拦截了他们的邮件。
Have some respect for those who are promoting your work and hosting you to remove the gum before the interview begins.
愿新春美景与欢乐常伴随你!

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

单词discourse 联想记忆:
Local-level work experience will advantageous for applicants, with personnel with more than two years of experience at this level given some advantage.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

注册人数:388人
But shipments to other destinations fared far worse, particularly those to re-exporter Hong Kong, which saw the dollar value of exports from China contract 26.3 per cent year on year to $33.84bn. Shipments to EU countries also fell 4.7 per cent to $33.5bn, while those to Japan dropped 5.5 per cent to $11.27bn.
2016年重庆市GDP增长了10.7%,达到了1.76万亿元人民币。贵州和西藏分别实现了10.5%和10%的GDP增长。
As the new iPhone continues to smash its own launch records, Mr Cook has unveiled products such as Apple Watch and Apple Pay that take the iPhone maker into the realms of fashion and finance, recapturing a spirit of innovation that many feared had died with Jobs. In the process, Apple’s valuation this year has grown by almost as much as Google’s entire market capitalisation.
adj. 接收能力强的,愿意接受的,感官的

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 贷款租房,叫好还要叫座
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

其中涉嫌售假的占比近45%,同比去年上升18.2%。消费者差评、频繁退货、投诉案例也很多。部分商家通过虚假低价的商业陷阱来促销商品。
The contiguous United States set a temperature record in 2012, a year of scorching heat waves and drought. But, mostly because of the unusual chill in the East, 2014 was only the 34th warmest year on record for the lower 48 states.
这句话最流行的变体是“别迷恋姐,姐只是个传说。”

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Stand: Apple CEO Tim Cook fought for workplace protection for the LGBT community
如果你是一个腼腆的人,那么一开始坐在前排可能会让你有点不自在。但是,我向你保证,这是接受老师传授的内容的最好的办法之一。你也可以听得更清楚。不用伸长脖子,你就可以看到黑板上所有的内容。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

In the most significant change in methodology since this ranking was first published in 2005, the FT now collects information about alumni’s first jobs after graduation. These data are used in conjunction with information about their current jobs, three years later. This allows the FT to calculate their salary increase since graduation — a new ranking criterion — as well as their career progress (see methodology).
第一次出现在人体内。禽类可能是病毒来源。Appeared for the first time in humans. It caused illness in two children in Hong Kong, with poultry being the probable source.
manifest显示,证明+o表名词,“人,物或状态”→宣言,声明

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

A Times reporter, Denise Grady, went inside an operating room to observe an experimental technique to treat severe spina bifida in a 24-week-old fetus. The doctors performing the surgery hope it will result in superior outcomes for children born with the disorder. Their first 28 surgeries have seen good results so far. Jan. 14 is the due date for the mother who was the subject of the article.
n. 鼓励
More recently, however, General Motors made a self-driving car in 1958 that adjusted its steering wheel based on the alternating currents given off by a wire placed inside the road. While the vehicle did actually drive itself, it does not qualify as the first autonomous vehicle because it depended on wires placed inside the ground. The world's first autonomous vehicle was made by S. Tsugawa and several of his colleagues at Japan's Tsukuba Mechanical Engineering Laboratory. However, German engineer Ernst Dickinson is regarded as the pioneer of the autonomous car. In 1987, he developed the VaMoRs which was capable of traveling more than 90 kilometers per hour (55 mph) for about 20 kilometers (12 mi). Seven years later, he made the VaMP, which could recognize road signs, know its own position in a lane, detect other vehicles, and even decide when to change lanes. And a year after that, he and his team made another autonomous vehicle which traveled from Germany to Denmark. The vehicle had a maximum speed of 180 kilometers per hour (111 mph) and was controlled by a human for about 5 percent of the journey.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 王府井步行街将延长
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

7. Amy Adams - $13.5 million

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 不负韶华 携手前行
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Welcome, and before we begin – please accept our apologies. Your four-hour nightmare wait at passport control should not be taken as a symptom of Britain's contempt for foreigners. It is merely a symptom of a woeful lack of spending on a key aspect of travel infrastructure in the run-up to a hugely important event. In other words, it's the government that hates you. Don't worry, they hate us too.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Influenced by the current economic situation, and resource relocation in China's financial market, the banking industry is away from the high-speed growth period, the expert added.
胡润表示,王健林今年已将集团旗下的地产公司从港交所退市,希望该公司能在上海或深圳交易所实现更高的估值。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Vegetable price growth more than doubled to 13 per cent year on year, helping push food inflation to 3 per cent, up from 2.7 per cent in September.
他有能力向球迷们展示接下来的计划吗?——不管是什么计划。在又一个无论场内场外都丑陋的赛季后,尼克斯球迷当然有理由知道上述两个问题的答案。
Thirty-six Chinese brands have made it onto the list this year. Among them, eight are in the top 100, including the State Grid Corporation of China (36), the Industrial and Commercial Bank of China (ICBC) (40), Tencent (43), China Central Television (CCTV) (62), Haier (76), China Mobile (79), Huawei (81) and Lenovo (90).
在你学习的时候,你要留意会考到的内容,并快速写下实践问题。在笔记本电脑上新建一个文件夹,并将你的问题添加进去。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

与此同时,居住在近百万套租金管制型公寓里的纽约人应该准备好,于明年(2015年——译注)6月在奥尔巴尼放手一搏,那个时候,租金管制法就要到期了。保障房的倡导者们希望看到这样一项规定的撤销——该规定允许业主在租金达到每月2500美元(约合人民币1.6万元)的情况下,取消对空置单元的租金管制。
特朗普几乎是教科书式的煽动家。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

distract
在NBA,很少人能防得住罗斯。那么,你可以想象,在罗斯的高中年代,有着和现在一样的NBA身板,要防住他更是天方夜谭。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

德国总理默克尔的年收入为21.84万欧元(约合24.2万美元)。德国总理的薪水在今年三月初上调2%,并将于明年二月继续上调2%。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Tuesday’s event at Apple’s new Cupertino headquarters is expected to reveal its much-anticipated 10th-anniversary iPhone, offering significant upgrades to the smartphone’s display, camera and overall design.
Zheng Gang, a member of the CPPCC National Committee and deputy mayor of Danzhou city, Hainan province.
单词elite 联想记忆:
7.无人机

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

It is a timely warning. His findings, he writes, “point to a heightened risk of emerging market crises in the coming years as the Fed continues to normalise interest rates”.
Elsewhere, Dua Lipa, who was up for three gongs, took home the Best New Artist award. While Harry Styles might have a reputation for being one of the most stylish members of One Direction, the Sign of the Times singer had his crown stolen by surprise MTV EMAs newcomer and former band mate, ZAYN.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

在2013年的这次调查中,东京重新获得“全球最贵城市”的头衔。瑞士苏黎士由于汇率波动在去年名列榜首,但今年由于政府采取了控制汇率措施,在榜单上下滑至第七。日本大阪成为全球第二贵的城市。
SAN JUAN, Puerto Rico (AP) — Puerto Rico’s new governor was sworn in Monday as the U.S. territory prepares for what many believe will be new austerity measures and a renewed push for statehood to haul the island out of a deep economic crisis.
福布斯全球2000强是一个囊括全球最大最具有实力的上市公司的综合榜单,我们的衡量指标为营收、利润、资产和市场价值。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

当晚的最高价来自唯一的一位欧洲电话出价人。此人以910万英镑购得约翰·康斯特布尔(John Constable)令人钦佩但很难让人喜爱的1824年纵向风景画《水闸》(The Lock)的1825年缩小版,这幅画从1855年起一直由一个英国家族私藏。
《中国文化遗迹》杂志是一本新创立的期刊,专门把发表在《文物》杂志上的原创文章翻译成英文。其创刊号上就发表了这座1700年墓地的发现。
Female and male participants typically have similar profiles at the start of their EMBA.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

年龄:46
对家长而言,整天抱着孩子非常费劲,尤其是孩子越来越大、越来越重的时候。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 如何躲过二手房交易中的那些坑
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

We learned about a warehouse that is like a mausoleum for endangered species.
It’s wall-to-wall pure pop heaven, crackling with originality and dark humor, teeming with action sequences so perfectly timed and executed you almost want to run out of the theater on the spot so you can call a friend and rave about it — but you wouldn’t dare leave your seat because you wouldn’t want to miss a frame of this brilliant, pulse-quickening gem.
节目9 相声《这事儿不赖我》,曹云金 刘云天

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

By investing deep in the industrial fabric of the country, from the coastal cities of Tianjin and Shanghai to the new industrial frontiers of the Western provinces of Shaanxi and Sichuan, from the processing of rare metals to the manufacturing and assembly of complex aircraft parts, China is adding substance to formand showing the world that, as far as its commercial aerospace achievements are concerned, the best is yet to come.
“谁来支付由此产生的成本呢?”纽约合作公寓和共管公寓委员会(Council of New York Cooperatives and Condominiums)的主席马克·J·卢森堡(Marc J. Luxemburg)表示,“这会给许多楼盘带来真真切切的成本。”

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Song “Happiness” (Mao A’Min)
I am calling this the Wan Long prize, after the Chinese meat magnate who once uttered the clearest sentence ever spoken by a CEO: “What I do is kill pigs and sell meat.” Mr Wan will surely approve of my winner, a BNSF railway executive who told a conference: “We move stuff from one place to another.”
calend一天+ar表名词,“人,物”→日历

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

With Westbrook playing such a hands-on, high-usage role and Victor Oladipo already locked in on a high-dollar extension, Payne needed to prove he could be an off-ball threat or a lead guard on the second unit.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

汇丰银行经济学家屈宏斌表示,汇丰银行的调查结果表明中国制造业正在失去增长势头,预计中国政府会采取措施对抗经济放缓。
谷歌英国的搜索结果分为热门趋势搜索榜和搜索次数排行榜。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

adj. 令人厌烦的
Other Chinese companies that filed a large number of patents included ZTE, Alibaba, Xiaomi, BYD and Haier, all of which are rapidly expanding into Europe.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

2016年,担忧和愤怒主导了英国和美国这两个最重要、稳定、悠久的民主政体的政治情绪。
Overall, St Gallen’s alumni report a 95 per cent satisfaction level, 2 percentage points more than the alumni from London Business School and WHU Beisheim.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

"It's not sustainable growth because they're not being rented out and they're pricing people in the local market out of buying."
Leadership

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Inarritu said: "I forgot to thank all the native Americans who made this film possible. I cannot say how surprised I am and how proud I am to have survived this film with all these fellows."

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

The pair stand on opposite sides backstage and memorize the winners to avoid having to write them down and have revealed in the past how they carry out rigorous checks to ensure they have stuffed the envelopes correctly. It is believed Ruiz and Cullinan are ordered to destroy the duplicate cards as the presentation goes on, so by the time Best Picture is awarded, the only envelopes left are the two for Best Picture.
中国保监会表示“面临复杂多变的市场环境”,上半年实现资金运用收益仅2944.82亿元人民币,下降42.32%。
Though Hand was British Petroleum's SVP of Global Brand, Marketing and Innovation, for several years, she's on a much more environmentally friendly mission today. Project Frog aims to revamp the construction industry with simple-to-build spaces (they takes days, rather than months to construct) that consume about 50% less energy than traditional buildings for sectors like education and healthcare. Hand's plan seems to be working: revenue is expected to more than double this year.
She is now so successful that her mother has hired a security team who monitor the star 24/7.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Buyers and Sellers

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

5. 杜克大学福库商学院
“这可能影响他们一生。”
12. 最有希望的迹象。有段时间,你会觉得现状已经改善了,人们可以公开大声谈及业内的歧视现象。维奥拉·戴维斯(Viola Davis)出来说话,詹妮弗·劳伦斯(Jennifer Lawrence)公开谈起,自己比片中的合作男星片酬少。“我不想被视为‘难搞’或者‘被宠坏了’,”她在简报《伦尼》(Lenny)中为许多人发言,其中包括许多薪酬更低的人们。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: “曹园”违建 初步查明
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

根据Interbrand2016年全球最佳品牌报告显示,该榜单的前十名还包括微软、丰田汽车公司、IBM、三星电子有限公司、亚马逊、梅塞德斯-奔驰和通用电气公司。
预计新一代iPhone中,将至少有一款采用人脸识别技术,这种图像捕捉技术能够感知深度,并追踪人脸及表情。随着苹果与Facebook和Snapchat等公司争夺用户的关注度,新一代iPhone将增加一系列包括猴子和机器人的新表情符号,其动画表情能够反映iPhone用户的脸。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

榜单前十名中的其它外国影片为《变形金刚5:最后的骑士》、《摔跤吧!爸爸》、《加勒比海盗5:死无对证》和《金刚:骷髅岛》。
罗宾哈丁(Robin Harding)

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

The Disaster Artist is part buddy movie, part show-business fable, and part behind-the-scenes DVD featurette.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

哈佛大学连续16年位居榜首,斯坦福大学和剑桥大学仍分别位列第二、第三名。
Everything Else
Scott Brooks gets leeway as he learns his roster, and injuries continue to play too big a role. But I just can't fathom why this team is so much worse than the playoff team from a couple years back. The other piece is that it's unlikely the Wizards can conceivably be bad enough to get a top-five pick.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Those born after 1995 tend to make more varied choices and are likely to combine work with their hobbies.
《中国文化遗迹》杂志是一本新创立的期刊,专门把发表在《文物》杂志上的原创文章翻译成英文。其创刊号上就发表了这座1700年墓地的发现。
New Year's greetings and best wishes!
The state-sponsored purchasing managers' index fell from 50.8 in October to 50.3 in November, the lowest reading since March. Any level above 50 indicates expansion.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

There has also always been a certain fluidity to this concept of whiteness. Irish and Italian immigrants to the United States, and Jews in Britain, were once seen as separate from the white national majority, and are now generally considered part of it, benefiting from racial privilege. At the same time, Jews’ white skin did not protect them from being cast as outsiders by some of Mr. Trump’s supporters who have circulated anti-Semitic memes on social media.
“We weren’t looking to throw the bums out, as they might say about an election. We were just really impressed with a flood of new powertrains, ” says Drew Winter, WardsAuto World Editor-in-Chief. “What was great yesterday might be less impressive tomorrow because engine technology is changing so rapidly.”

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Online registration will end on Oct. 24. The exam will be held on Nov. 27 in major Chinese cities.
THE AMERICANS (FX, Jan. 28) Season 3 of this terrific blend of Cold War spy thriller and family drama begins with Washington’s K.G.B. contingent feeling the weight of the Soviet war in Afghanistan. Frank Langella joins the cast as the new handler for the show’s husband-and-wife agents, replacing Margo Martindale’s Claudia. (Making its premiere eight days later: NBC’s “Allegiance,” about Russian spies embedded in the United States. Huh.)
他原以为只要有人点击这个广告,就会给他捐献一点钱。但是实际上,每当有人点击这个链接的时候,他都需要付费。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 全国房贷利率连续18个月上涨
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About this collection

“New Yorkers have been waking up and realizing this long period of prosperity has wreaked a little bit of havoc on things that we think of as classic New York,” said Simeon Bankoff, the executive director of the Historic Districts Council, noting that 2015 will mark the 50th anniversary of the New York City landmarks preservation law. “Things we always thought were going to be there are just closing left and right.”
“如果听到苹果CEO是同性恋,能帮助一些人努力直面自我,或者给一些感到孤独的人带来慰藉,或者激励人们坚持自己的平等权利,那么这值得我用个人隐私来交换,”他在为《彭博商业周刊》(Bloomberg Businessweek)的10月号撰文时写道。

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