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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

特朗普会发动美中贸易战吗?
As you graduate, my friends, remember what lies ahead of you is a world overflowing with beauty and potential; not just in the form of office corridors or Wall Street but a real, throbbing world, full of many mysteries and heady experiences. A number of us miss this simple truth.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

For: Oldman's seemingly effortless embodiment of the wartime leader has won almost universal
Jackdaw Research的简?道森(Jan Dawson)表示,最近几个月“他表现得更加意气风发和充满自信”。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

斯坦福大学商学院校友的平均薪资最高,为19.5万美元,但总体而言,排在前15名之内的MBA课程在收入、职业发展和满意度方面都非常接近。除了一所学校外,这些商学院的校友平均薪资均超过15万美元,与就读MBA以前的收入相比,薪资上涨了大约100%。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 南京黏土砖瓦窑退出历史舞台
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

[tr?'din?l]

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

There was no immediate word from the Romney camp on the reported results。
创业会对创业者的个人生活造成严重影响。虽然上面的建议对创业成功至关重要,但从精神和身体上照顾好自己同样是必要的。锻炼、睡眠和饮食是确保你成功执行这些策略的关键要素。这些要素能够帮助你调整心态,获得动力,拓展人际关系。
You're the best present I ever received.你是我所收到的最好的礼物。
Hailed as one of the greatest films of all time, Taxi Driver tells the story of a depressed ex-Marine who attempts to assassinate a senator after being rejected by a woman he admires. While the titular taxi driver, Travis Bickle, lives a chaotic life filled with drug dealers and prostitutes, his story was never meant to be an unrealistic fantasy. Rather, it meant to expose the very real warning signs of a would-be gunman.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

projected
随着中国实力的抬升,其最好的友敌美国占了前10名的另一半。第5名和第9名分别是伯克希尔哈撒韦保险公司以及富国银行,这两家公司相较去年的排名均上升4位。
联想首席执行官杨元庆
达奇斯说:阿迪达斯在今年的12个月里增加了3400万名新粉丝。公司把粉丝们带动了起来,粉丝们一整年都在进行积极的讨论,公司因而从中受益。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

toxic

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The US box office, which includes totals from Canada, hit $11.1 billion, an 8 percent increase year-over-year, and was credited to several smash hits, including Jurassic World ($652 million domestically), Avengers: Age of Ultron ($459 million) and Inside Out ($356 million).

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

We will deepen rural reform.
There are always one or two coworkers in the office that most people can't stand. But if you don't like most of your coworkers, chances are your days aren't very enjoyable because you have to work with them day in and day out. If you can't stand most of your coworkers, it's time to think about finding a company whose employees you mesh with better.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

课程安排:为期一周的课前培训后,学员在每周末的星期五和星期六交替上课,周五晚提供住宿。最后一个学期需住校学习两周,其余时间在线完成学习任务。
But some people might just remember the mustaches.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

胡润表示,王健林今年已将集团旗下的地产公司从港交所退市,希望该公司能在上海或深圳交易所实现更高的估值。
Though Hand was British Petroleum's SVP of Global Brand, Marketing and Innovation, for several years, she's on a much more environmentally friendly mission today. Project Frog aims to revamp the construction industry with simple-to-build spaces (they takes days, rather than months to construct) that consume about 50% less energy than traditional buildings for sectors like education and healthcare. Hand's plan seems to be working: revenue is expected to more than double this year.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

单词productive 联想记忆:
Song “Fire In The Winter”(Kenji Wu and Dream Chorus)
Yet if “Mad Men” showed us anything (besides how cool a skinny suit could look, and that wide ties really were not a good men’s wear moment), it is that the decade chronicled was a complicated, often unhappy, occasionally destructive time.
SplashData公司首席执行官摩根-斯莱恩说:“不幸的是,虽然最新的一部星球大战系列电影很精彩,但使用‘starwars’这个密码却很危险。”

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

达成一个全球性气候协议的下一次大尝试,将是在来自世界各地的谈判代表今年12月聚集巴黎的时候。气候变化问题的政治活动人士上周五不失时机地引用2014年的温度记录为证,表明采取强有力行动的必要性。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

8. Sturgill Simpson “Metamodern Sounds in Country Music” (High Top Mountain) A throwback progressive hunkered down with a whip-smart band: country music has seen this before. But on his breakthrough second album, Sturgill Simpson made it a pliable trademark, grounded at every turn by his winning, seen-it-all baritone.
3. Dan Weiss “Fourteen” (Pi Recordings) There’s so much in “Fourteen,” the album-length composition by the drummer Dan Weiss: meticulous chamber maneuvers; avant-garde yowling; wordless vocals of new-music and northern Indian pedigree. More impressive than the expansive frame of reference is the fact that Mr. Weiss, marshaling about a dozen of his peers, spins it all into a flowing fabric.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

The block chain has such rich potential that there is an initiative underway to create additional “side chains,” though there is controversy around that idea. “We don’t really want to mess with the main block chain right now,” says Adam Ludwin, CEO of Chain, a block chain API that makes it easier to create bitcoin applications. “It works, we don’t want to break it.”

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Belgium, for example, has less than a tenth of the population of Russia, its rival in the group stage, but is regarded as a far greater threat. And then there is Uruguay, which despite fewer than 4 million citizens -- barely a sixth of the population of greater S?o Paulo -- is one of the teams Brazil would least like to meet on its way to the final. How is this so?

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

就算油价在2015年有可能反弹,但是油价几乎不可能再短期内回到100美元一桶,除非在世界主要产油地区发生广泛的地缘政治危机。所以这份礼物将在2015年得到持续并且长久的促进美国经济的加快复苏。
吉尔伯特说:“我们很容易看到,在当下的市场中,领头羊们都处在相当脆弱危险的地位。看看他们在每款新设备上做出创新的速度,我们可以很明显地发现这一点。”
facilitate
12. 《教师》,导演:那达夫·拉皮德。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Yes. There are plenty of positives: earnings, economic growth, and US tax cuts. But they are already known. Stocks look ridiculously expensive by historical standards, but that tells us nothing about short-term moves. Ultimately, it comes down to liquidity, which has driven markets since they emerged from the crisis in 2009. If all goes according to plan, central banks will be decreasing their balance sheets, and removing liquidity, by the end of 2018. If they go through with this, the odds are that the S&P will stall. But even a tiny tremor could make the bankers blink. Expect the momentum to continue.
That possibility was backed up by a list of top-tier cities the statistics bureau began tracking recently
Companies do have black lists. It's not written down anywhere but it's a list of people they'd be happy to get rid of if the opportunity arises. If you feel invisible, if you're getting bad assignments, if your boss is ignoring you, or if they move your office, you're probably on it.
As the calendar flips to December it’s not too early to think about the inevitability of tanking. Who should do it, who should wait, and who shouldn’t ever consider it. Flanns and Zillz discuss.
Lisa Stone

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 线上还是线下家居品牌站队难
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

持续推进大众创业、万众创新。
这会吓走一些人,这些人不了解你更好。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

adj. 故意的,有意的;打算中的 n. 已订婚者 v.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
From the themed collection: 建材卖场发力备战双节
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

首先,我们来回顾一下这些南美国家吧。东道主巴西队肯定是第一个要提到的。时间倒流18个月,巴西在这段时间一直在努力,但是对人称“大菲尔”(Big Phil)的斯科拉里(Scolari)的任命起到了作用。他让球队重新拾回失去的信念。在2013年联合会杯决赛中,3:0大胜西班牙的战果让诸多专业人士震惊,也在突然之间,巴西让人们对他们寄予了厚望。虽然你无法驳斥这样的比分,但是我们依旧想知道巴西是否有实力赢得此次世界杯。人们预计,内马尔(Neymar)也将放出“魔法”大招,但是他们还是想依靠弗雷德来进球。这不是对弗雷德无礼,不过,在1994以及2002年,巴西之所以能够赢得世界杯还是依靠于罗纳尔多和罗马里奥领衔前线的成功,而这两位也被誉为世界杯的传奇人物。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

4.厨师
Consumer Electronics Show
“We will see a lot of headlines about [emerging market export growth] picking up in the first half of 2017,” says Bhanu Baweja, head of EM cross asset strategy at UBS, who believes EM exports will show year-on-year growth of between 8 and 13 per cent in dollar terms in the first quarter of this year, “a complete postcode away” from the negative numbers currently being reported.
萨姆·史密斯是一个风格多变的男人,他可以在奥蒂斯·雷丁、艾瑞莎·弗兰克林和雷·查尔斯以及像艾米·怀恩豪斯和阿黛尔这样的现代偶像的风格中随意转换。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 海南部分湿地遭房地产开发蚕食
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

vt. 包含,容纳,克制,抑制
D'Aloisio himself strives to maintain a bubble of normalcy. He dates the same girl he did before the whirlwind hit. And though he's stopped attending school-he's too busy to sit in class while overseeing Summly's development-he still gets his work from his teachers and meets with them regularly. He cherishes the fact that his circle of friends knows little of his life as a budding industrialist. When I met him, he was about to head to Greece for a weeklong vacation with a pack of high school pals.
However, five Beijing-based travel agents said they were still selling South Korea tours for March, as was China’s largest online travel company Ctrip. Representatives at the top three state-owned airline carriers in China told Bloomberg they had not received instructions to halt ticket sales to the country.
每个员工都想偶尔得到上级的鼓励,优秀的老板们懂得认识和感激员工贡献的重要性。这并不意味着要对员工们作出一定的薪资奖励,而是合理的有意义的表达感激之情。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

中国人民勤劳智慧,有着追求美好生活的不竭动力,政府就是要创造环境,让人民群众创业创新的热情持久不衰。
《使女的故事》

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

福特是硅谷一家软件开发公司的创始人,他认为“或许需要从根本上重建我们的经济规则”,以减轻机器人和自动化的进步带来的冲击。他提出建立保底的基本收入,即“公民红利”,作为一项根本性的补救措施。
Western states dominate the best states for projected job growth. Only two, Florida and Georgia, of the top 10 are located east of the Mississippi River. Rounding out the top five are Colorado (2.6% annual projected growth), North Dakota (2.5%) and Florida (2.5%).
年龄:46
更强的是设计公司Ideo的全球董事总经理伊恩?罗伯茨(Iain Roberts),他问了一个我一点都不感兴趣的问题:“怎样激发人们去洞察潜在机动性或多模式需求?”
7月,美国国家航空航天局(NASA)宣布发现了一颗类地行星,激发了中国人的想象。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

“这让编辑以为文章发送给了该学科真正的评审人。我们与真正的评审人进行调查和沟通后,他们确认并没有对论文做过评审。
“Insead enormously boosted our intercultural experience,” said one alumni survey respondent from Switzerland. “It is a place to learn global culture better than anywhere else.”
据斯派克回忆,一天,拍摄工作结束后,另一位编剧詹妮弗·克里滕登在走廊叫住他,问:"你一定要这样吗?你确定这样不会毁了朱莉娅的前程吗?"考虑到当年朱莉娅凭此剧获得艾美奖,我们不妨说这场舞戏其实让这位女演员在演艺事业上更进了一步。为了怀旧,您不妨抽空再去回顾一下伊莱恩和她著名的"伊莱恩舞步"。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

达奇斯说:强大的财务性能和一系列新的特性使得邻客音成为2012年吸引用户的公司。这样的吸引力有助于公司在2013年从专业的业务网络转向活跃的交流平台。
Martin Ford, author of The Rise of the Robots , received the 30,000 Financial Times and McKinsey Business Book of the Year Award at a ceremony in New York on Tuesday.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

8月24日
['sep?reit]
二年级的佩恩,作为一个乐透秀,因为脚伤很多时间不能上场,并且没有表现出作为投手或者防守球员的一点点进步。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 有了超材料 童话将变成现实
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Erle Spratt, who manages M&G’s Asia property fund, an open-ended investment vehicle, says it is risky to invest directly because assets are not easy to find and price. “It is a very difficult market to buy assets in for investors like us, because developers have very substantial holdings and they tend not to sell,” he says.
Six regions recorded GDP growth less than 7 percent, with China's north-eastern rust belt Liaoning province at the bottom with negative growth.
自2014年10月以来,新兴市场出口额(以美元计算)一直下降,即使没有2008年至2009年全球金融危机期间的下降幅度极端,也比当时持续的时间要长得多,如第一张图表所示。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 检方揭秘让“黑中介” 无所遁形
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

We will make continued progress in building a Healthy China.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

在过去的12个月里,这位22岁的T台女王兼真人秀明星赚得2200万美元,首次登顶福布斯模特收入榜。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 央行三天净投放4000亿元
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Developer activity is also at a fever pitch. According to the contributor graph at GitHub, the total number of contributions to bitcoin’s master code in November was the highest it had been since spring 2012. Bitcoin is also the 31st “most forked repository” on GitHub—”forks” are basically proposed or in-progress alterations to core code—out of more than 900,000. In other words, for developers, bitcoin is trending. The number of open jobs currently posted at bitcoin companies also underscores developer interest: it’s at 105, which is close to the all-time high in September of 137, according to Bitcoin Pulse, which monitors such trends.
n. 笔画,击打,一笔(画)连续的动作,中风,

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

So take a look. I sincerely hope you enjoy reading them as much as I liked selecting and editing them.
谎言4:太感谢了!我很喜欢!说谎原因:告诉别人他们送的礼物一团糟会让我看起来像是冷血的混蛋。
[spu:n]
The memes were shared as part of a private Facebook chat where admitted students in the class of 2021 shared edgy jokes as part of a "just-because-we-got-into-Harvard-doesn't-mean-we-can't-have-fun kind of thing", an admitted student told the Harvard Crimson.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

74个重点城市细颗粒物(PM2.5)年均浓度下降9.1%;
清华-欧洲工商管理学院的EMBA项目始于2007年,并于2012年进入英国《金融时报》排行榜,首次入围就直接冲至第四名。此后两年,该项目先后排名第二和第三,并最终在今年拔得头筹。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Perhaps in response, at the start of 2017, China's media regulator quietly began including service fees charged by online ticketing companies when reporting box-office figures.
UK schools account for more than a third of all graduates from the top 50 pre-experience programmes and not only attracted nearly half of all female students but also almost half of all international students. Indeed, 94 per cent of students enrolled in a UK MiF pre-experience programme in 2014 were from overseas. About 85 per cent of these students were from outside the European Economic Area, including 55 per cent of the overall number from mainland China.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 广州去年3881套保障房竣工
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

And, thanks to Artnet and other databases that list auction results, wealthy people who buy art have become all too aware of how hard it is to make a profit on old masters.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

At school, even in kindergarten, you teach us to behave in the world. You teach us: not to fight with others, to respect others, to clean up our mess, not to hurt other creatures, to share - not be greedy. 在学校,甚至在幼稚园,你们大人教我们如何处世,你们告诉我们不要打架,要尊重对方。找出答案,解决矛盾。去分享,而不是贪婪。
The surviving cat, since named Trooper, has recovered and found a new home.
You see all kinds of grisly, hairy characters on the Tube but few commuters would've expected to see a pack of pandas on the platform.
10.Firefly was Inspired by Gettysburg

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

美国就业市场笼罩着重重阴云──特别是遭遇增税、减支双重打击的可能性,即“财政悬崖”。[qh]
Spotify, the music streaming service, plans to list existing private shares directly on the New York Stock Exchange as soon as the fourth quarter rather than doing a formal IPO, while other large, well-known tech companies for now were seen as more likely prospects for 2018, bankers said.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

是的,另一个萨克拉门托不该垫底的原因就是:费城今年有权和他们交换选秀权。因此,国王队完全没可能得到状元签,而且他们得到前三签位的可能性也很低。
时间:2010-03-14 编辑:alex
n. 冰箱

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

[.sju:p?'vin]
hospitality
奥巴马的另两条上榜推文是在他卸任时发布的。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

单词triangle 联想记忆:
But if the U.S. can avert that Washington-made crisis, the outlook for workers finding jobs is actually looking pretty good for next year. For one thing, the damage of superstorm Sandy will have to be repaired, meaning jobs in construction and retail. Businesses, meanwhile, which have held off investing and hiring because of uncertainty over the fiscal outlook, might finally open their wallets. That means more jobs, too.[qh]

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

老虎要入眠,鸟儿要降落;
2.德语:增长了22.2%
These contraptions, including a nano-sized car, are so small that they’re invisible to the human eye.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 前7月中国22城市“卖地”收入翻番
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

While the WeChat use of the "post-90s" generation has slightly decreased, from 94.1 percent to 86.6 percent.
While newcomer to the list Ariel Foxman, who was appointed managing editor at Time Inc.’s In Style in September 2008, isn’t a regular on a television show as of yet, his fashion director Hal Rubenstein is now a judge onLifetime’s Blush: The Search for the Next Great Make-up Artist. And Foxman’s publication led the way in number of advertising pages, boasting over 1,000 during the first half of 2009.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

还有哪对系列电影的荧幕情侣可以像《暮光之城》的克里斯汀?斯图尔特和罗伯特?帕丁森这样成功开创戏路呢?两个人都成为了影坛名角。帕丁森在最新作品《好时光》中延续了他近年来这种让人几乎认不出的造型风格。在《迷失Z城》中,他把自己打扮成胡子蓬乱的眼镜男,如今他又把头发染成亚麻色,变身为一个试图在纽约完美做案,结果却让患有发育性残疾的弟弟(本?萨弗迪饰)被捕的银行抢劫犯。他试图用盗取的钱来给弟弟交保释金,结果麻烦接踵而至。很多的麻烦。除了饰演弟弟一角外,本?萨弗迪还和自己的哥哥约书亚?萨弗迪共同执导了这部电影。《好时光》入围了今年戛纳电影节的主竞赛单元,参与角逐金棕榈奖。该片于11月3日在日本上映,11月17日在英国和爱尔兰上映,11月23日在希腊上映。(资料来源:A24制片公司)
201001/93725.shtml
At a Senate committee hearing on extrajudicial executions in the Philippines, Ronald Dela Rosa said 712 people had been killed in police anti-narcotics operations since July 1, the day after Mr Duterte assumed the presidency, while 1,067 deaths were being investigated as drug-related vigilante killings.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 租房“坑”多 小心中招
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Roula Khalaf

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

The fastest-rising sector is apparel, driven by Nike in sportswear as people pay more attention to health and fitness, and Zara, whose fast fashion is becoming increasingly popular in China.
在新兴市场出口量方面,巴韦贾不排除增长约4%至5%的可能性。但是,尽管与近年来相比这将是一种温和改善,但这一增长速度仍“处于长期分布中的最差25%区间,甚至可能是最差20%区间”,因为过去25年的年增长率中值约为7%。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 一天涨50万 听抢房者的亲历故事
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

We will accelerate the development of emerging industries.
1.It wasn’t me! – Because some things just aren’t worth taking credit for。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

This sign varies from company to company. You must keep in mind that we are in a recession and if sales are down but the company isn't in jeopardy, this sign may not apply to you. However, if business is down to the point where it looks like the company is going to go under, start looking for a new job NOW! (See also: 20 Signs that a Pink Slip is Coming)
Under the Skin is just so visually free and uninhibited that there is an intense dark, destructive sexiness in everything about it – quite apart from the hilarious, bizarre, mesmeric eroticism of the film itself. It is a work of subcutaneous potency. It gets under your skin.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

你可能从未想过一根皮带可以与人工智能相结合,但Belty做到了,并使它看起来很时尚。这个belty会让你不自觉就觉得,“为什么我需要这个?”然后你想可能会是,“如果是黑客入侵,他们把它系得很紧我不能呼吸该怎么办?”第一个问题是合理的;第二个问题有些牵强,但如果它让你三思而后买这个产品,这并不是一件坏事。
"If all these train tickets were lined up, they would circle the earth 7 times," said Zhu Jiansheng, deputy director of the Institute of Computing Technologies with the Chinese Academy of Railway Sciences, where the ticketing system was developed.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

年度故事将是纽约对911主谋穆罕默德(Khalid Sheikh Mohammed)的审判。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

5. What are my core values? What is important to you as an individual? Is it family, health, spirituality, work, etc.? Make sure that you are living in alignment with what matters most to you.
That was a less marked jump than the 3 percentage point rise from August to September, however, suggesting recent curbs to property purchases may be having some effect.
上述消息源还称,苹果将在明年10月发布一款12.9英寸的平板电脑,“目标消费群是北美的教育市场(和)……生产商是广达电脑(Quanta Computer)”。有报道称,三星也在研发尺寸在12至13英寸之间的平板电脑,而现在看来,“这些大尺寸平板电脑将极大地影响超极本需求”几乎是板上钉钉的事了。新款“iPad Max”,搭载整合了键盘和电池的新款外壳之后,实际上就是一台笔记本电脑,很有可能在高中生和大学生之中成为主流产品——这一人群需要比现有iPad和iPad Mini产品更好的内容创造工具。
如果没有别的,很明显,夏天交易期并不代表NBA赛季的停止,它只是换了个档而已。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

5.Celebrity Mocks Mao

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

在美国股市整体被“踩下刹车”的情况下,特斯拉的股价还在一路狂飙。自今年年初至今,其股价已经上涨了80%,目前每股约262美元,接近该公司有史以来的最高值,市值达到320亿美元。
深化农村改革。
I formerly had an Android device (even though I have had a MacBook since 2009 – weird, I know). After switching this summer, I quickly realized the power of iPhone “Reminders.” Each time a reminder is due, your iPhone buzzes and displays a pop-up. You can snooze it or mark as completed. In addition, you can set up recurring reminders, which are perfect for remembering to mail estimated quarterly tax payments, renewing subscriptions, running payroll and other things you tend to forget.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Andy Murray's US Open victory and Olympic gold medal helped him to become the most searched-for British Olympian.
2) I often talk to strangers 0 1 2 3 4

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

其实我一直都在等你提到篮网队的处境,既然你没说,那就我来说吧。林书豪已经因腿筋受伤缺阵几周了。他们是唯一有摆烂权利但是不摆烂的球队!
我们就是要用政府的“痛”换来企业的“顺”,让企业轻装上阵,提高竞争力。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

The details of her character are being kept under wraps.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

8. Ford Motor
2. 宾夕法尼亚大学沃顿商学院
Rios is no stranger to hard work. She moved to the U.S. from El Salvador when she was a child. She graduated at the top of her high school class and raised a family while putting herself through college. She was not intimidated when she started Nation Waste Inc. At just 22, months after graduating from the University of Houston, she took out loans and purchased two trucks, jumping into the male-dominated waste-removal industry. Today, her Houston-based company has 24 full-time employees. "It is pretty amazing when I look back and see, I started as a little girl entering the United States with my parents and now I am truly living the American dream," says Rios.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

"No one really knows how (end times) would look and how God would bring it about," Cox said.
White anxiety has fueled this year’s political tumult in the West: Britain’s surprising vote to exit the European Union, Donald J. Trump’s unexpected capture of the Republican presidential nomination in the United States, the rise of right-wing nationalism in Norway, Hungary, Austria and Greece.
担忧是围绕向下流动(downward mobility)和文化变迁,而愤怒是针对移民和冷漠的精英。
v. 燃烧,面红,爆发

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Roth, 60, is a professor at Harvard University in Boston. Shapley, 89, is a professor emeritus at University of California Los Angeles.
将学习放在最重要的位置

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

西门子(Siemens)去年破纪录了,通过将医疗部更名为Healthineers一举斩获两项大奖。该公司不仅因为将两个单词生拼硬造出另一个无比蹩脚的新词从而荣获“马丁?卢克斯奖”(Martin Lukes prize),同时还凭借现场视频中一位倾情演唱的CEO和身着氨纶紧身衣卖力献舞的员工们,摘得史上最尴尬企业歌曲的金牌。
With executive compensation in the U.S. rising and the income gap only getting bigger, it's refreshing to see a CEO who cares about more than his own paycheck. Lenovo(LNVGF) Chief Executive Yang Yuanqing announced in September for the second year in a row that he would share at least $3 million of his bonus with roughly 10,000 of his workers. The generous decision was a product of the personal computer maker's record sales that year. The average worker payout is equal to roughly a month's pay for the typical city worker in China, according to Bloomberg News.
全国居民人均可支配收入实际增长6.3%;

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Julia Hartz
It was the spring of hope, it was the winter of despair…

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